mnp13 wrote:Do you titer her? That's a good way to check for immunity - and I would definitely do that before I bring her into a shelter environment. There are many people diseases that are contagious before symptoms show up, so knowing that her immunity is as high as possible is not a bad idea.
plebayo wrote:mnp13 wrote:Do you titer her? That's a good way to check for immunity - and I would definitely do that before I bring her into a shelter environment. There are many people diseases that are contagious before symptoms show up, so knowing that her immunity is as high as possible is not a bad idea.
I agree with running a vaccine titer. Then you know what her coverage is. I personally think we over vaccinate and a dog who has been vaccinated most of its life should be covered. If you do run a titer please share the results/your experience because it might shed more light on the whole vaccine argument. I mean it obviously varies dog to dog but it still would be interesting!
What does your titer tell you? The RFFIT test can be used in two ways: to determine a RVNA titer (e.g., 1:5) or to determine a value for RVNA concentration (e.g., 0.5 IU). The IU stands for international unit and is calculated from the titer by comparing it against a standard reference serum. If you do not have RVNA present in your serum it will not neutralize the virus and the titer will be LESS THAN 1:5 (the 1:5 diluted serum did not prevent the virus from infecting the cells). RVNA antibody will neutralize rabies virus to an “endpoint titer” – to a specific dilution where the virus is neutralized. For example, if you have a little RVNA in your serum low dilutions (e.g. 1:5 or 1:25) will neutralize the virus, but higher dilutions will not. In contrast, if you have a lot of antibody in your serum the virus will be neutralized by high dilutions of your serum (e.g. 1:1000 or 1:7000) and not infect the cells. Therefore the further your serum can be diluted and still neutralize virus, the more RVNA you have in your serum. Current ACIP regulations recommend evidence of complete neutralization at serum dilution of 1:5 is considered an adequate response to rabies vaccination (1). If your serum diluted to 1:5 cannot neutralize virus a booster dose may be recommended (for people determined to be at risk of rabies virus exposure - see ACIP recommendations). In summary, the bigger the denominator in the reported titer, the more antibody in your blood (e.g., a titer of 1:125 has more antibody than a titer of 1:5 because it still neutralized at a much higher dilution) and a reported RVNA titer of greater than 1:5 is considered adequate.
LMM wrote:Hey Michelle, how were you able to get a waiver for the rabies? Because of his titer count? I would like to get one for Four but I understood it to be state law and even a veterinary waiver doesn't hold up. Is that not right?
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